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Synthesis of a functionalized Cyclohepten-one from Erythronic acid-4-lactone

Pitsch, W. ; Russel, A. ; Zabel, M. ; König, B.



Abstract

A convenient two-step synthesis of a functionalized and chiral cyclohepten-one 4, which may serve as a useful building block in synthesis, is reported. The X-ray structure analysis of the intermediate hemiacetal 2 reveals the presence of a single anomer in the solid state, that equilibrates rapidly in solution.


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