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Design, Synthesis, and Evaluation of a Biomimetic Artificial Photolyase Model

Wiest, O., Harrison, C.B., Saettel, N. J., Cibulka, R., Sax, M. and König, B. (2004) Design, Synthesis, and Evaluation of a Biomimetic Artificial Photolyase Model. J. Org. Chem. 69, 8183 – 8185.

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Two new artificial photolyase models that recognize pyrimidine dimers in protic and aprotic organic solvents as well as in water through a combination of charge and hydrogen-bonding interactions and use a mimic of the flavine to achieve repair through reductive photoinduced electron transfer are presented. Fluorescence and NMR titration studies show that it forms a 1:1 complex with pyrimidine ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
15549785PubMed ID
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:6247
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