Kruppa, M., Bonauer, C., Michlová, V. and König, B. (2005) Enhanced Peptide β-Sheet Affinity by Metal to Ligand Coordination. J. Org. Chem. 70, 5305 - 5308.
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Abstract
A histidine-coordinating metal complex substituted with methoxypyrrole amino acids (MOPAS) as a peptide β-sheet binder shows high affinity for a H2N−His-Leu-Leu-Val-Phe-OMe pentapeptide in DMSO solution. Within the complex, a β-sheet conformation is induced into the pentapeptide by weak intra-assembly interactions with the MOPAS units.
Export bibliographical data
| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 2005 | ||||
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König | ||||
| Projects: | GRK 760, Graduiertenkolleg Medizinische Chemie | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 6259 |
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