Maity, P., Zabel, M. and König, B. (2007) Tetrahydrofuran Cα-Tetrasubstituted Amino Acids: Two Consecutive β Turns in a Crystalline Linear Tripeptide. J. Org. Chem. 72, 8046 – 8053.
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Abstract
The synthesis of tetrahydrofuran Cα-tetrasubstituted amino acids (TAAs) and their effect on the conformation in small peptides are reported. The synthesis starts from the protein amino acid methionine, which is protected at the C and N terminus and converted into the corresponding sulfonium salt by alkylation. Simple base treatment in the presence of an aryl aldehyde leads to the formation of ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 2007 | ||||
| Institutions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König Chemistry and Pharmacy > Institut für Anorganische Chemie > Arbeitskreis Prof. Dr. Nikolaus Korber | ||||
| Projects: | GRK 760, Graduiertenkolleg Medizinische Chemie | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 6281 |
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