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Enantio- and Diastereoselective Syntheses of Cyclic Cα-Tetrasubstituted α-Amino Acids and Their Use to Induce Stable Conformations in Short Peptides (Review)

Maity, P. ; König, Burkhard



Zusammenfassung

Cα-Tetrasubstituted α-amino acids are widely used to design and prepare peptides and peptide mimics with constrained conformations. Subcategories of these compounds are cyclic Cα-tetrasubstituted α-amino acids, in which both α-substituents are covalently connected. This survey presents recent advances in the synthesis and application of cyclic Cα-tetrasubstituted α-amino acids in a systematic ...

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