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Recognition of the Helix-Loop-Helix Domain of the Id Proteins by an Artificial Luminescent Metal Complex Receptor

Kiewitz, S. D. ; Kruppa, M. ; Riechers, A. ; König, B. ; Cabrele, C.


Synthetic agents specifically interacting with a protein interface are important not only for the better understanding of protein dimer or complex formation but also for medical applications. Here we describe the recognition of the helix-loop-helix (HLH) dimerization domain of the Id proteins by an artificial luminescent receptor containing two binding sites for a Lewis acid and a Lewis base, ...


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