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Exogenous Schwann Cells Migrate, Remyelinate and Promote Clinical Recovery in Experimental Auto-Immune Encephalomyelitis

Klein, Robyn ; Zujovic, Violetta ; Doucerain, Cédric ; Hidalgo, Antoine ; Bachelin, Corinne ; Lachapelle, François ; Weissert, Robert ; Stadelmann, Christine ; Linington, Chris ; Evercooren, Anne Baron-Van



Zusammenfassung

Schwann cell (SC) transplantation is currently being discussed as a strategy that may promote functional recovery in patients with multiple sclerosis (MS) and other inflammatory demyelinating diseases of the central nervous system (CNS). However this assumes they will not only survive but also remyelinate demyelinated axons in the chronically inflamed CNS. To address this question we investigated ...

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