Startseite UR

Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy

Friedrich, Felix W. ; Wilding, Brendan R. ; Reischmann, Silke ; Crocini, Claudia ; Lang, Patrick ; Charron, Philippe ; Müller, Oliver J. ; McGrath, Meagan J. ; Vollert, Ingra ; Hansen, Arne ; Linke, Wolfgang A. ; Hengstenberg, Christian ; Bonne, Gisèle ; Morner, Stellan ; Wichter, Thomas ; Madeira, Hugo ; Arbustini, Eloisa ; Eschenhagen, Thomas ; Mitchell, Christina A. ; Isnard, Richard ; Carrier, Lucie



Zusammenfassung

Hypertrophic cardiomyopathy (HCM) is characterized by asymmetric left ventricular hypertrophy, diastolic dysfunction and myocardial disarray. HCM is caused by mutations in sarcomeric genes, but in 40 of patients, the mutation is not yet identified. We hypothesized that FHL1, encoding four-and-a-half-LIM domains 1, could be another disease gene since it has been shown to cause distinct myopathies, ...

plus


Nur für Besitzer und Autoren: Kontrollseite des Eintrags
  1. Universität

Universitätsbibliothek

Publikationsserver

Kontakt:

Publizieren: oa@ur.de
0941 943 -4239 oder -69394

Dissertationen: dissertationen@ur.de
0941 943 -3904

Forschungsdaten: datahub@ur.de
0941 943 -5707

Ansprechpartner