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Novel Serial Positive Enrichment Technology Enables Clinical Multiparameter Cell Sorting

Carvalho, Luzia Helena ; Stemberger, Christian ; Dreher, Stefan ; Tschulik, Claudia ; Piossek, Christine ; Bet, Jeannette ; Yamamoto, Tori N. ; Schiemann, Matthias ; Neuenhahn, Michael ; Martin, Klaus ; Schlapschy, Martin ; Skerra, Arne ; Schmidt, Thomas ; Edinger, Matthias ; Riddell, Stanley R. ; Germeroth, Lothar ; Busch, Dirk H.



Zusammenfassung

A general obstacle for clinical cell preparations is limited purity, which causes variability in the quality and potency of cell products and might be responsible for negative side effects due to unwanted contaminants. Highly pure populations can be obtained best using positive selection techniques. However, in many cases target cell populations need to be segregated from other cells by ...

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