Zusammenfassung
Augmentation of standard chemotherapy with peripheral blood stem cells (PBSC) rescue is a standard treatment strategy. However, in pediatric patients weighing less than 20?kg, the collection of PBSC presents a challenge. We report our experience with nine pediatric patients weighing between 4.33 and 19.9?kg and a total of 23 PBSC collection aphereses. None of our patients experienced any major ...
Zusammenfassung
Augmentation of standard chemotherapy with peripheral blood stem cells (PBSC) rescue is a standard treatment strategy. However, in pediatric patients weighing less than 20?kg, the collection of PBSC presents a challenge. We report our experience with nine pediatric patients weighing between 4.33 and 19.9?kg and a total of 23 PBSC collection aphereses. None of our patients experienced any major complications. We conclude that PBSC apheresis in children is a safe method. It should be based on a standardized procedure that includes the determination of clinical and laboratory parameters and appropriate monitoring. Pediatr Blood Cancer 2012; 58: 627629. (c) 2011 Wiley Periodicals, Inc.
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