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High resolution ultrasound including Elastography and Contrast-Enhanced Ultrasound (CEUS) for early detection and characterization of liver lesions in the humanized tumor mouse model

Wege, A.K. ; Schardt, K. ; Schaefer, S. ; Kroemer, A. ; Brockhoff, G. ; Jung, E.M.



Zusammenfassung

Purpose: In this study we investigated the sensitivity of high resolution ultrasound (HRU) in the detection of small liver tumors and its microcirculation in a humanized tumor mouse model (HTM). These mice develop a complete human immune system and human breast cancer growth in the liver which allows the investigation of antibody based immunotherapies under human like conditions. Method: HTM were ...

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