Callaerts, Patrick ; Halder, Partho ; Chen, Yi-chun ; Brauckhoff, Janine ; Hofbauer, Alois ; Dabauvalle, Marie-Christine ; Lewandrowski, Urs ; Winkler, Christiane 
; Sickmann, Albert ; Buchner, Erich
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | PLoS ONE |
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| Verlag: | PUBLIC LIBRARY SCIENCE |
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| Ort der Veröffentlichung: | SAN FRANCISCO |
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| Band: | 6 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 12 |
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| Seitenbereich: | e29352 |
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| Datum: | 2011 |
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| Institutionen: | Biologie und Vorklinische Medizin > Institut für Zoologie |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1371/journal.pone.0029352 | DOI |
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| Stichwörter / Keywords: | POLYACRYLAMIDE GELS; EH DOMAIN; PROTEIN; MELANOGASTER; THERAPEUTICS; GENE; BRUCHPILOT; HOMOLOGY; THERAPY; ASCITES; |
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| Dewey-Dezimal-Klassifikation: | 500 Naturwissenschaften und Mathematik > 590 Tiere (Zoologie) |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 64305 |
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Web of Science
Zusammenfassung
The Wuerzburg Hybridoma Library against the Drosophila brain represents a collection of around 200 monoclonal antibodies that bind to specific structures in the Drosophila brain. Here we describe the immunohistochemical staining patterns, the Western blot signals of one- and two-dimensional electrophoretic separation, and the mass spectrometric characterization of the target protein candidates ...
Zusammenfassung
The Wuerzburg Hybridoma Library against the Drosophila brain represents a collection of around 200 monoclonal antibodies that bind to specific structures in the Drosophila brain. Here we describe the immunohistochemical staining patterns, the Western blot signals of one- and two-dimensional electrophoretic separation, and the mass spectrometric characterization of the target protein candidates recognized by the monoclonal antibodies aa2 and ab52 from the library. Analysis of a mutant of a candidate gene identified the Drosophila homolog of the Epidermal growth factor receptor Pathway Substrate clone 15 (Eps15) as the antigen for these two antibodies.
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