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Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts

Jiao, Li ; Berrington de Gonzalez, Amy ; Hartge, Patricia ; Pfeiffer, Ruth M. ; Park, Yikyung ; Freedman, D. Michal ; Gail, Mitchell H. ; Alavanja, Michael C. R. ; Albanes, Demetrius ; Beane Freeman, Laura E. ; Chow, Wong-Ho ; Huang, Wen-Yi ; Hayes, Richard B. ; Hoppin, Jane A. ; Ji, Bu-tian ; Leitzmann, Michael F. ; Linet, Martha S. ; Meinhold, Cari L. ; Schairer, Catherine ; Schatzkin, Arthur ; Virtamo, Jarmo ; Weinstein, Stephanie J. ; Zheng, Wei ; Stolzenberg-Solomon, Rachael Z.



Abstract

To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes. In a pooled analysis of primary data of seven prospective cohorts including 458,070 men and 485,689 women, we identified 2,454 patients with incident pancreatic cancer during an average 6.9 years of ...

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