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Possible association of Down syndrome and exstrophy–epispadias complex: report of two new cases and review of the literature

Reutter, Heiko ; Bökenkamp, Arend ; Ebert, Anne-Karolin ; Rösch, Wolfgang ; Boemers, Thomas M. ; Nöthen, Markus M. ; Ludwig, Michael



Zusammenfassung

In the past, several midline defects have been associated with Down syndrome (DS) on a regular basis, e.g. heart defects, cleft lip and palate, neural tube defects, omphalocele and anal atresia. The exstrophy-epispadias complex (EEC) represents a rare midline defect, rarely described in association with DS. Here, we report on the co-occurrence of DS and EEC in two, so far, unreported cases and ...

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