Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | International Journal of Medical Microbiology |
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| Verlag: | ELSEVIER GMBH, URBAN & FISCHER VERLAG |
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| Ort der Veröffentlichung: | JENA |
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| Band: | 297 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 5 |
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| Seitenbereich: | S. 393-400 |
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| Datum: | 2007 |
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| Institutionen: | Medizin > Lehrstuhl für Immunologie |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1016/j.ijmm.2007.03.005 | DOI |
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| Stichwörter / Keywords: | TOLL-LIKE RECEPTORS; NECROSIS-FACTOR-ALPHA; INNATE-IMMUNE-SYSTEM; NEGATIVE REGULATOR; INFLAMMATORY RESPONSE; SEPTIC PERITONITIS; GAMMA-INTERFERON; CROSS-TOLERANCE; DEFICIENT MICE; PROTECTS MICE; |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 68874 |
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Web of Science
Zusammenfassung
Inflammation is the basic process by which tissues of the body respond to infection. Activation of the immune system normally leads to removal of microbial pathogens, and after resolution of the inflammation immune homeostasis is restored. This controlled process, however, can be disturbed resulting in disease. Therefore, many Studies using infection models have investigated the participating ...
Zusammenfassung
Inflammation is the basic process by which tissues of the body respond to infection. Activation of the immune system normally leads to removal of microbial pathogens, and after resolution of the inflammation immune homeostasis is restored. This controlled process, however, can be disturbed resulting in disease. Therefore, many Studies using infection models have investigated the participating immune mechanisms aiming at possible therapeutic interventions. Defined model substances such as bacterial lipopolysaccharide (endotoxin) have been used to mimic bacterial infections and analyze their immune stimulating functions. A complex network of molecular mechanisms involved in the recognition and activation processes of bacterial infections and their regulation has developed from these studies. More complex infection models will now help to interpret earlier observations leading to the design of relevant new infection models. (c) 2007 Elsevier GmbH. All rights reserved.
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