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Fast quantitative determination of diuretic drugs in tablets and human urine by microchip electrophoresis with native fluorescence detection

Tolba, Kamal ; Belder, Detlev



Zusammenfassung

Microchip electrophoresis (MCE) with native fluorescence detection has been applied for the fast quantitative analysis of pharmaceutical formulations. For this purpose, methods for fast separation and sensitive detection of the unlabeled diuretic drugs, amiloride, triamterene, bendroflumethiazide (BFMTZ), and burrietanide were developed. An epifluorescence setup was used enabling the coupling of ...

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