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A locus on chromosome 10 influences C-reactive protein levels in two independent populations

Broeckel, Ulrich ; Hengstenberg, Christian ; Mayer, Bjoern ; Maresso, Karen ; Gaudet, Daniel ; Seda, Ondrej ; Tremblay, Johanne ; Holmer, Stephan ; Erdmann, Jeanette ; Glöckner, Christian ; Harrison, Michael ; Martin, Lisa J. ; Williams, Jeff T. ; Schmitz, Gerd ; Riegger, Guenter A. J. ; Jacob, Howard J. ; Hamet, Pavel ; Schunkert, Heribert



Zusammenfassung

High sensitivity C-reactive protein (hsCRP) is an independent risk factor for cardiovascular disease, such as stroke or coronary artery disease. Genetic factors influence significantly the inter-individual variability of hsCRP. The aim of this study was to identify genomic regions influencing hsCRP levels. A genome scan was performed in two independent studies of Caucasian populations, namely 513 ...

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