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Long-Term Effectiveness of Azathioprine in IBD Beyond 4 Years: A European Multicenter Study in 1176 Patients

Holtmann, Martin H. ; Krummenauer, Frank ; Claas, Christina ; Kremeyer, Kristina ; Lorenz, Dirk ; Rainer, Olivia ; Vogel, Iris ; Böcker, Ulrich ; Böhm, Stephan ; Büning, Carsten ; Duchmann, Rainer ; Gerken, Guido ; Herfarth, Hans ; Lügering, Norbert ; Kruis, Wolfgang ; Reinshagen, Max ; Schmidt, Jan ; Stallmach, Andreas ; Stein, Jürgen ; Sturm, Andreas ; Galle, Peter R. ; Hommes, Daan W. ; D’Haens, Geert ; Rutgeerts, Paul ; Neurath, Markus F.



Zusammenfassung

In Crohn's disease the optimal duration of azathioprine treatment is still controversial and for ulcerative colitis only limited data are available to support its efficacy. Charts of 1176 patients with IBD from 16 European centers were analyzed. Flare incidences and steroid dosages were assessed for the time before and during treatment and after discontinuation. Within the first 4 years, ...

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