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Influence of α-Hydroxylation of Glycolipids on Domain Formation in Lipid Monolayers

Windschiegl, Barbara ; Steinem, Claudia



Abstract

By means of fluorescence and scanning force microscopy (SFM), we investigated the phase behavior of lipid monolayers composed of a mixture of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, sphingomyelin, and cholesterol (5/2/3) with either alpha-hydroxylated or nonhydroxylated galactocerebroside. Fluorescence images of lipid monolayers at the air-water interface demonstrate that, independent ...

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