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2,3,4,5- Tetrahydro- 1-Benzoxepines a Novel Class of Anti-Implantation Agents

Tandon, Vishnu ; Rai, Sanjay



Zusammenfassung

5-Substituted 2,3,4,5-Tetrahydro-1-benzoxepine derivatives have been synthesized as novel anti-implantation agents. The synthesized compounds were evaluated for their anti-implantation activity in mature female Sprague-Dawley rats. The most active compounds in this series 10d and 11d, are 67% active in preventing implantation in rats at 10 mgkg(-1) dose. We also found that the other compounds of ...

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