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Basic fibroblast growth factor enhances PPARγ ligand‐induced adipogenesis of mesenchymal stem cells

Neubauer, Markus ; Fischbach, Claudia ; Bauer-Kreisel, Petra ; Lieb, Esther ; Hacker, Michael ; Tessmar, Joerg ; Schulz, Michaela B. ; Goepferich, Achim ; Blunk, Torsten



Zusammenfassung

Mesenchymal stem cells (MSCs) are capable of differentiating into a variety of lineages, including bone, cartilage, or fat, depending on the inducing stimuli and specific growth and differentiation factors. It is widely acknowledged that basic fibroblast growth factor (bFGF) modulates chondrogenic and osteogenic differentiation of MSCs, but thorough investigations of its effects on adipogenic ...

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