Herrmann, Wolfgang Artur ; von Mohrenfels, Christoph Winkler ; Lohmann, Chris Patrick
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | Cornea |
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| Verlag: | LIPPINCOTT WILLIAMS & WILKINS |
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| Ort der Veröffentlichung: | PHILADELPHIA |
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| Band: | 23 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 8 |
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| Seitenbereich: | S. 825-827 |
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| Datum: | 2004 |
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| Institutionen: | Medizin > Lehrstuhl für Augenheilkunde |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1097/01.ico.0000126331.84852.f6 | DOI |
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| Stichwörter / Keywords: | DENSITY-LIPOPROTEIN DEFICIENCY; Tangier disease; cortical opacification; corneal sensation; confocal microscopy |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 71189 |
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Web of Science
Zusammenfassung
Purpose: Tangier disease is an autosomal recessive disorder in which cholesterol-rich lipids are deposited at various tissues of the body including the cornea. In this case report, the corneal changes in a patient with Tangier disease are described. Methods: A 72-year-old patient who was diagnosed with Tangier disease 25 years before received a complete eye examination including confocal ...
Zusammenfassung
Purpose: Tangier disease is an autosomal recessive disorder in which cholesterol-rich lipids are deposited at various tissues of the body including the cornea. In this case report, the corneal changes in a patient with Tangier disease are described. Methods: A 72-year-old patient who was diagnosed with Tangier disease 25 years before received a complete eye examination including confocal microscopy and Cochet-Bonnet esthesiometry. Results: Slit-lamp biomicroscopy and confocal microscopy showed bilateral corneal opacifications caused by lipid accumulation. Confocal microscopy showed that pathologic changes in the cornea in Tangier disease are limited to the stroma. Neither a reduced corneal sensation nor lid abnormalities as previously described in Tangier disease were found. Conclusion: Confocal microscopy helps to identify corneal changes in the stroma caused by Tangier disease easily missed in a Slit-lamp examination. The ocular manifestations of Tangier disease do not necessarily include a reduced corneal sensitivity and lid abnormalities.
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