Gleich, Otto ; Hamann, Ingo ; Klump, Georg M. ; Kittel, Malte ; Strutz, Jürgen
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | NeuroReport |
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| Verlag: | LIPPINCOTT WILLIAMS & WILKINS |
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| Ort der Veröffentlichung: | PHILADELPHIA |
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| Band: | 14 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 14 |
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| Seitenbereich: | S. 1877-1880 |
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| Datum: | 2003 |
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| Institutionen: | Medizin > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1097/00001756-200310060-00024 | DOI |
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| Stichwörter / Keywords: | GAP DETECTION; MERIONES-UNGUICULATUS; INFERIOR COLLICULUS; COCHLEAR NUCLEUS; AGE; RECOGNITION; PRESBYCUSIS; ACUITY; LEVEL; MOUSE; aging; auditory pathways; auditory perception; auditory processing disorder; GABA agonists; presbycusis |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 72022 |
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Web of Science
Zusammenfassung
Elderly humans often not only experience peripheral hearing loss but also suffer from more central deficits in temporal auditory processing affecting speech perception. Impaired auditory temporal resolution has also been observed in old rodents. Other studies have demonstrated a reduction of GABAergic function in the auditory pathway of old animals. Here we test the hypothesis that deficits in ...
Zusammenfassung
Elderly humans often not only experience peripheral hearing loss but also suffer from more central deficits in temporal auditory processing affecting speech perception. Impaired auditory temporal resolution has also been observed in old rodents. Other studies have demonstrated a reduction of GABAergic function in the auditory pathway of old animals. Here we test the hypothesis that deficits in the GABAergic system affect central auditory processing. Our data suggests that pharmacological augmentation of the GABAergic system ameliorates impaired temporal auditory processing in the gerbil and might be a strategy for the treatment of at least some forms of central hearing loss in humans.
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