Gege, Christian ; Geyer, Armin ; Schmidt, Richard R.
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | European Journal of Organic Chemistry |
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| Verlag: | WILEY-V C H VERLAG GMBH |
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| Ort der Veröffentlichung: | WEINHEIM |
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| Band: | 2002 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 15 |
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| Seitenbereich: | S. 2475 |
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| Datum: | 2002 |
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| Institutionen: | Chemie und Pharmazie > Institut für Organische Chemie |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1002/1099-0690(200208)2002:15<2475::AID-EJOC2475>3.0.CO;2-M | DOI |
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| Stichwörter / Keywords: | LACTONEO-SERIES ANTIGENS; CELL-ADHESION; METHYLTHIOMETHYL ETHERS; BINDING; GLYCOSPHINGOLIPIDS; GLYCOSYLATION; GLYCOLIPIDS; PROTECTION; COMPLEX; LE(X); carbohydrates; Lewis X; glycosylation; NMR spectroscopy; polyvalency |
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| Dewey-Dezimal-Klassifikation: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 72826 |
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Zusammenfassung
Bivalent Lewis X (Le(x)) oligosaccharides were synthesised in order to study the conformational details of carbohydrate clusters by NMR spectroscopy. To this end, two Le(x) trisaccharide moieties (1) were covalently linked through the 6-hydroxy group or through the anomeric oxygen of GlcNAc to yield dimers 2 and 3, respectively. The two Le(x) halves of the model saccharide 2 exhibited ...
Zusammenfassung
Bivalent Lewis X (Le(x)) oligosaccharides were synthesised in order to study the conformational details of carbohydrate clusters by NMR spectroscopy. To this end, two Le(x) trisaccharide moieties (1) were covalently linked through the 6-hydroxy group or through the anomeric oxygen of GlcNAc to yield dimers 2 and 3, respectively. The two Le(x) halves of the model saccharide 2 exhibited cooperativity in calcium binding. Three different lactosides served as control compounds for NMR titration with calcium chloride.
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