Reinhold, D. ; Kähne, T. ; Steinbrecher, A. ; Wrenger, S. ; Neubert, K. ; Ansorge, S. ; Brocke, S.
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | Biological Chemistry |
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| Verlag: | WALTER DE GRUYTER & CO |
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| Ort der Veröffentlichung: | BERLIN |
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| Band: | 383 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 7-8 |
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| Datum: | 2002 |
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| Institutionen: | Medizin > Lehrstuhl für Neurologie |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1515/BC.2002.123 | DOI |
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| Stichwörter / Keywords: | TRANSFORMING GROWTH-FACTOR-BETA-1 TGF-BETA-1; MESSENGER-RNA EXPRESSION; PWM-STIMULATED PBMC; IN-VIVO; CD26; LYMPHOCYTES; INHIBITORS; GROWTH; SUPPRESSION; SECRETION; autoimmune diseases; CD26; dipeptidyl peptidase IV; T cell activation |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 72869 |
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Web of Science
Zusammenfassung
Activated T lymphocytes express high levels of dipeptidyl peptidase IV (DP IV)/CD26. Recent studies support the notion that DP IV may play an important role in the regulation of differentiation and growth of T lymphocytes. This article gives a short overview on DP IV/CD26 expression and effects on immune cells in vitro and in vivo. A major focus of this review are clinical aspects of the function ...
Zusammenfassung
Activated T lymphocytes express high levels of dipeptidyl peptidase IV (DP IV)/CD26. Recent studies support the notion that DP IV may play an important role in the regulation of differentiation and growth of T lymphocytes. This article gives a short overview on DP IV/CD26 expression and effects on immune cells in vitro and in vivo. A major focus of this review are clinical aspects of the function of CD26 on hematopoietic cells and the potential usage of synthetic DP IV inhibitors as therapeutics in inflammatory disorders.
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