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Sensitivity of the negative mucosal potential to the trigeminal target stimulus CO2

Thürauf, Norbert ; Günther, Michael ; Pauli, Elizabeth ; Kobal, Gerd



Abstract

CO2 is frequently used in an experimental pain model and in imaging studies investigating the central processing of trigeminal nociceptive information because of its specific trigeminal stimulation properties. The aim of the current study was (1) to investigate the sensitivity of the NMP to small increments of CO2 stimulus concentrations (3% CO2 v/v) and (2) to characterize the sensory input of ...

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