Zusammenfassung
Background and Objectives. Anti-inflammatory actions of ciclopirox,an antifungal agent, have been described previously. We assessed the effectiveness of ciclopirox in the treatment of viral warts. Patients/Methods. Twenty-three immunocompetent patients (age 9-61 years) with com mon warts at the hands, feet and in the face resistant to conventional therapy were treated. Following keratolysis with ...
Zusammenfassung
Background and Objectives. Anti-inflammatory actions of ciclopirox,an antifungal agent, have been described previously. We assessed the effectiveness of ciclopirox in the treatment of viral warts. Patients/Methods. Twenty-three immunocompetent patients (age 9-61 years) with com mon warts at the hands, feet and in the face resistant to conventional therapy were treated. Following keratolysis with a salicylic acid-containing patch, an 8% ciclopirox lacquer was applied 1-2 times daily. At the beginning and the end of the treatment lesions were photographed and the time span (minimum 4 weeks) until complete resolution was documented. Results. In 7 patients complete remission, and in 12 patients partial remission was achieved. Only 4 patients did not show any effect under topical ciclopirox treatment (mean duration of therapy 3.2 +/-2.1 months). The overall response rate was 82.6%. Local side effects like erythema or pruritus were not reported. Conclusion. Our data suggest that a ciclopirox lacquer may be helpful in the treatment of com mon warts. However, the data have to be confirmed in a randomized controlled trial in the future.
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