A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability‐nonexchangeability method

URN to cite this document:: urn:nbn:de:bvb:355-epub-759335
DOI to cite this document:: 10.5283/epub.75933

Daniells, Libby

; Mozgunov, Pavel ; Bedding, Alun ; Jaki, Thomas

License: Creative Commons Attribution 4.0
PDF - Published Version
(2MB)

Date of publication of this fulltext: 18 Mar 2025 10:07

Alternative links to fulltext:DOI Publisher

Details

Preview

Indexed in

Export bibliographical data

Abstract

Recent innovation in trial design to improve study efficiency has led to the development of basket trials in which a single therapeutic treatment is tested on several patient populations, each of which forms a basket. In a common setting, patients across all baskets share a genetic marker and as such, an assumption can be made that all patients may have a homogeneous response to treatments. ...