Benchmarking of survival outcomes following Haematopoietic Stem Cell Transplantation (HSCT): an update of the ongoing project of the European Society for Blood and Marrow Transplantation (EBMT) and Joint Accreditation Committee of ISCT and EBMT (JACIE)

Saccardi, Riccardo ; Putter, Hein ; Eikema, Dirk-Jan ; Busto, María Paula ; McGrath, Eoin ; Middelkoop, Bas ; Adams, Gillian ; Atlija, Marina ; Ayuk, Francis Ayuketang ; Baldomero, Helen ; Beguin, Yves ; de la Cámara, Rafael ; Cedillo, Ángel ; Balari, Anna María Sureda ; Chabannon, Christian ; Corbacioglu, Selim ; Dolstra, Harry ; Duarte, Rafael F. ; Dulery, Rémy ; Greco, Raffaella ; Gusi, Andreu ; Hamad, Nada ; Kenyon, Michelle ; Kröger, Nicolaus ; Labopin, Myriam ; Lee, Julia ; Ljungman, Per ; Manson, Lynn ; Mensil, Florence ; Milpied, Noel ; Mohty, Mohamad ; Oldani, Elena ; Orchard, Kim ; Passweg, Jakob ; Pearce, Rachel ; de Latour, Régis Peffault ; Poirel, Hélène A. ; Rintala, Tuula ; Rizzo, J. Douglas ; Ruggeri, Annalisa ; Sanchez-Martinez, Carla ; Sanchez-Guijo, Fermin ; Sánchez-Ortega, Isabel ; Trnková, Marie ; Ferreiras, David Valcárcel ; Wilcox, Leonie ; de Wreede, Liesbeth C. ; Snowden, John A.

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Alternative Links zum Volltext:DOIVerlag

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Details

Dokumentenart:	Artikel
Titel eines Journals oder einer Zeitschrift:	Bone Marrow Transplantation
Verlag:	SPRINGERNATURE
Ort der Veröffentlichung:	LONDON
Band:	58
Nummer des Zeitschriftenheftes oder des Kapitels:	6
Seitenbereich:	S. 659-666
Datum:	2023
Institutionen:	Medizin > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation
Identifikationsnummer:	Wert Typ 10.1038/s41409-023-01924-6 DOI
Stichwörter / Keywords:	INTERNATIONAL BENCHMARKING; COMORBIDITY INDEX; MANAGEMENT; VALIDATION; SYSTEM; CARE;
Dewey-Dezimal-Klassifikation:	600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
Status:	Veröffentlicht
Begutachtet:	Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:	Ja
Dokumenten-ID:	76300

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Zusammenfassung

From 2016 EBMT and JACIE developed an international risk-adapted benchmarking program of haematopoietic stem cell transplant (HSCT) outcome to provide individual EBMT Centers with a means of quality-assuring the HSCT process and meeting FACT-JACIE accreditation requirements relating to 1-year survival outcomes. Informed by previous experience from Europe, North America and Australasia, the ...

Zusammenfassung

From 2016 EBMT and JACIE developed an international risk-adapted benchmarking program of haematopoietic stem cell transplant (HSCT) outcome to provide individual EBMT Centers with a means of quality-assuring the HSCT process and meeting FACT-JACIE accreditation requirements relating to 1-year survival outcomes. Informed by previous experience from Europe, North America and Australasia, the Clinical Outcomes Group (COG) established criteria for patient and Center selection, and a set of key clinical variables within a dedicated statistical model adapted to the capabilities of the EBMT Registry. The first phase of the project was launched in 2019 to test the acceptability of the benchmarking model through assessment of Centers' performance for 1-year data completeness and survival outcomes of autologous and allogeneic HSCT covering 2013-2016. A second phase was delivered in July 2021 covering 2015-2019 and including survival outcomes. Reports of individual Center performance were shared directly with local principal investigators and their responses were assimilated. The experience thus far has supported the feasibility, acceptability and reliability of the system as well as identifying its limitations. We provide a summary of experience and learning so far in this 'work in progress', as well as highlighting future challenges of delivering a modern, robust, data-complete, risk-adapted benchmarking program across new EBMT Registry systems.

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