Schäfer, Hannah ; Mayr, Sarah ; Büttner-Herold, Maike ; Knorr, Karina ; Steinhelfer, Lisa ; Böger, Carsten A. ; Gschwend, Jürgen E. ; Heemann, Uwe ; Eiber, Matthias ; Schmaderer, Christoph ; Tauber, Robert
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | European Urology |
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| Verlag: | ELSEVIER |
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| Ort der Veröffentlichung: | AMSTERDAM |
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| Band: | 83 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 5 |
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| Seitenbereich: | S. 385-390 |
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| Datum: | 2023 |
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| Institutionen: | Medizin > Abteilung für Nephrologie |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1016/j.eururo.2022.05.025 | DOI |
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| Stichwörter / Keywords: | LU-177-DOTATATE; DOSIMETRY; TOXICITY; IMPACT; Lu-177-PSMA; Metastatic castration -resistant; prostate cancer; Prostate cancer; Radiation nephropathy; Radioligand therapy; Renal toxicity; Theranostics; Chronic kidney disease; Tubulotoxicity; Thrombotic microangiopathy |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 76357 |
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Web of Science
Zusammenfassung
Lutetium-177 prostate-specific membrane antigen (177Lu-PSMA) radioligand ther-apy is an option that is increasingly being used for treatment of metastatic castration-resistant prostate cancer. This delivers b-radiation to cells expressing PSMA and high accumulation of the radiopharmaceutical occurs in the kidneys. Here we report three cases of radiation nephropathy with severe chronic kidney ...
Zusammenfassung
Lutetium-177 prostate-specific membrane antigen (177Lu-PSMA) radioligand ther-apy is an option that is increasingly being used for treatment of metastatic castration-resistant prostate cancer. This delivers b-radiation to cells expressing PSMA and high accumulation of the radiopharmaceutical occurs in the kidneys. Here we report three cases of radiation nephropathy with severe chronic kidney disease induced by renal thrombotic microangiopathy following extensive treat-ment with 177Lu-PSMA radioligand therapy. (c) 2022 European Association of Urology. Published by Elsevier B.V. All rights reserved.
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