Association of Serum Afamin Concentrations With Kidney Failure in Patients With CKD: Findings From the German CKD Cohort Study

URN to cite this document:: urn:nbn:de:bvb:355-epub-765603
DOI to cite this document:: 10.5283/epub.76560

Kollerits, Barbara ; Kotsis, Fruzsina ; Schneider, Markus P. ; Schultheiss, Ulla T. ; Weissensteiner, Hansi ; Schönherr, Sebastian ; Forer, Lukas ; Meiselbach, Heike ; Wanner, Christoph ; Eckardt, Kai-Uwe ; Dieplinger, Hans ; Kronenberg, Florian ; Schiffer, Mario ; Prokosch, Hans-Ulrich ; Bärthlein, Barbara ; Beck, Andreas ; Reis, André ; Ekici, Arif B. ; Becker, Susanne ; Alberth-Schmidt, Ulrike ; Weigel, Anke ; Marschall, Sabine ; Schefler, Eugenia ; Walz, Gerd ; Köttgen, Anna ; Meder, Simone ; Mitsch, Erna ; Reinhard, Ursula ; Floege, Jürgen ; Saritas, Turgay ; Gross, Alice ; Schaeffner, Elke ; Baid-Agrawal, Seema ; Theisen, Kerstin ; Haller, Hermann ; Zeier, Martin ; Sommerer, Claudia ; Aykac, Mehtap ; Wolf, Gunter ; Busch, Martin ; Steiner, Andy ; Sitter, Thomas ; Krane, Vera ; Börner-Klein, Antje ; Bauer, Britta ; Oefner, Peter J.

; Gronwald, Wolfram ; Schmid, Matthias ; Nadal, Jennifer

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 14 Apr 2025 06:58

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Abstract

Rationale & objective: Afamin is a vitamin E-binding glycoprotein primarily expressed in the liver and kidney. This study investigated whether serum afamin concentrations are associated with kidney function and incident kidney failure. Study design: Prospective cohort study with 6.5 years follow-up. Setting & participants: 5,041 White patients enrolled in the German Chronic Kidney Disease ...