Impact of Liver and Kidney Function on Vitamin D3 Metabolism in Female and Male Patients Undergoing Allogeneic Hematopoietic Stem-Cell Transplantation

URN to cite this document:: urn:nbn:de:bvb:355-epub-768901
DOI to cite this document:: 10.5283/epub.76890

Weich, Laura ; Brummer, Christina ; Ghimire, Sakhila ; Peter, Katrin

; Althammer, Michael ; Babl, Nathalie

; Voll, Florian ; Bruss, Christina ; Hoering, Marcus ; Wallner, Stefan

; Siska, Peter J.

; Holler, Ernst ; Herr, Wolfgang ; Bruns, Heiko ; Heid, Iris M. ; Stark, Klaus J. ; Kreutz, Marina

; Matos, Carina

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 17 Jun 2025 17:08

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Abstract

We previously described that elevated levels of the active vitamin D3 metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) during the early phase of allogeneic hematopoietic stem-cell transplantation (HSCT) can predict one-year transplant-related mortality (1y-TRM). Given that the liver and kidneys are the primary organs responsible for the effective conversion of vitamin D3, we investigated whether ...