Zusammenfassung
There is no question that the TIGR/MYOC gene has captured the attention of glaucoma research. For the first time, a specific gene product has been identified that can be causative for glaucoma. Studies of TIGR/MYOC could provide the long-sought key for a better understanding of the pathogenesis of primary open-angle glaucoma (POAG). A substantial effort has been made over the past few years to ...
Zusammenfassung
There is no question that the TIGR/MYOC gene has captured the attention of glaucoma research. For the first time, a specific gene product has been identified that can be causative for glaucoma. Studies of TIGR/MYOC could provide the long-sought key for a better understanding of the pathogenesis of primary open-angle glaucoma (POAG). A substantial effort has been made over the past few years to understand the physiologic as well as structural roles of TIGR/MYOC, and their pathophysiologic and potential therapeutic relevance.