Interferon gamma modifies nanoparticle tropism and cell uptake

URN to cite this document:: urn:nbn:de:bvb:355-epub-775006
DOI to cite this document:: 10.5283/epub.77500

Remmert, Marius ; Konrad, Johannes

; Birringer, Jan

; Goepferich, Achim

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 05 Aug 2025 06:56

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Abstract

Interferon gamma (IFN-γ) challenges the ability of viruses to distinguish between target and off-target cells i.e. viral tropism. Due to the similarity of viruses and nanoparticles in shape and size, we hypothesized that the effect of IFN-γ on viruses also applies to virus-mimetic nanoparticles. Therefore, we determined the influence of IFN-γ on nanoparticle tropism and cell uptake. For our ...