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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-785622
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.78562
Schelker, Roland C. ; Fioravanti, Jessica ; Mastrogiovanni, Fabio ; Baldwin, Jeremy G. ; Rana, Nisha ; Li, Peng ; Chen, Ping ; Vadász, Timea 
; Spolski, Rosanne ; Heuser-Loy, Christoph ; Slavkovic-Lukic, Dragana ; Noronha, Pedro ; Damiano, Giuseppe ; Raccosta, Laura ; Maggioni, Daniela ; Pullugula, Sree ; Lin, Jian-Xin ; Oh, Jangsuk ; Grandinetti, Patrick ; Lecce, Mario ; Hesse, Leo ; Kocks, Emilia ; Martín-Santos, Azucena ; Gebhard, Claudia ; Telford, William G. ; Ji, Yun ; Restifo, Nicholas P. ; Russo, Vincenzo ; Rehli, Michael ; Herr, Wolfgang ; Leonard, Warren J. ; Gattinoni, Luca
; Spolski, Rosanne ; Heuser-Loy, Christoph ; Slavkovic-Lukic, Dragana ; Noronha, Pedro ; Damiano, Giuseppe ; Raccosta, Laura ; Maggioni, Daniela ; Pullugula, Sree ; Lin, Jian-Xin ; Oh, Jangsuk ; Grandinetti, Patrick ; Lecce, Mario ; Hesse, Leo ; Kocks, Emilia ; Martín-Santos, Azucena ; Gebhard, Claudia ; Telford, William G. ; Ji, Yun ; Restifo, Nicholas P. ; Russo, Vincenzo ; Rehli, Michael ; Herr, Wolfgang ; Leonard, Warren J. ; Gattinoni, Luca Zusammenfassung
High frequencies of stem-like memory T cells in infusion products correlate with superior patient outcomes across multiple T cell therapy trials. Herein, we analyzed a published CRISPR activation screening to identify transcriptional regulators that could be harnessed to augment stem-like behavior in CD8+ T cells. Using IFN-γ production as a proxy for CD8+ T cell terminal differentiation, LMO4 ...
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