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Data archive of Inhibition of (interstitial) P2Y<sub>6</sub> receptors attenuates fibrosis progression

URN zum Zitieren dieses Dokuments:
urn:nbn:de:bvb:355-epub-786001
DOI zum Zitieren dieses Dokuments:
10.5283/epub.78600
Forst, Anna-Lena ; Süß, Lena-Marie ; Süß, Anja ; Warth, Richard ; Broeker, Katharina A. E. ; Firmke, Bettina K. M. ; Tran, Linh Minh
[img]Anderes
list of all files uploaded
(46kB)
[img]Anderes
Fig1: .czi micoscopy files of kidneys used in Figure1
(177MB)
[img]Anderes
Fig.2: .czi files of fura2 measurements with FACS-sorted Pdgfrb+ fibroblasts
(10GB)
[img]Anderes
Fig 4.: LightCycler .l96 files and .czi micoscopy files of kidneys used in Figure 4
(17GB)
[img]Anderes
FIg. 5: LightCycler .l96 files and .czi micoscopy files of kidneys used in Figure 5
(31GB)
[img]Anderes
Fig. 3.: czi-files for Figure 3
(33GB)
Veröffentlichungsdatum dieses Volltextes: 18 Feb 2026 10:02


Zusammenfassung

Chronic kidney disease (CKD) affects over 850 million people worldwide and is characterized by progressive renal fibrosis driven by activated interstitial fibroblasts. Signaling by extracellular nucleotides and P2 receptors plays an important role in renal pathophysiology, yet its contribution to fibroblast activation and fibrosis remains poorly understood. Here, we investigated the expression ...

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