Botulinum toxin therapy of migraine and tension-type headache: comparing different botulinum toxin preparations

DOI to cite this document:: 10.5283/epub.818

Schulte-Mattler, W. J. ; Martinez-Castrillo, J. C.

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Date of publication of this fulltext: 05 Aug 2009 13:24

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Abstract

Most of the initial reports on botulinum toxin in tension-type headache (TTH) and in migraine were positive. Unfortunately, these results were not reproduced in well-designed, randomized controlled trials. So far, doses from 20 U (Botox) to 500 U (Dysport) have been studied in patients with chronic TTH, and doses from 16 to 200 U (Botox) in patients with migraine. Overall, there is no evidence ...