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The influence of endogenous surfactant on the structure and drug-release properties of Eudragit NE30D-matrixes

URN to cite this document:
Göpferich, Achim ; Lee, Geoffrey
Date of publication of this fulltext: 14 Aug 2009 11:46


The influence of an endogenous surfactant present in Eudragit NE30D on the structure and drug release (clenbuterol) properties of thin matrices has been examined. Both drug-free and drug-loaded matrices were found to be non-isotropic in structure, the former having a marbled appearance under the polarising light microscope, and the latter showing numerous needle-shaped crystals. At loading above ...


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