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The influence of endogenous surfactant on the structure and drug-release properties of Eudragit NE30D-matrixes

Göpferich, Achim and Lee, Geoffrey (1992) The influence of endogenous surfactant on the structure and drug-release properties of Eudragit NE30D-matrixes. Journal of Controlled Release 18 (2), pp. 133-144.

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Abstract

The influence of an endogenous surfactant present in Eudragit NE30D on the structure and drug release (clenbuterol) properties of thin matrices has been examined. Both drug-free and drug-loaded matrices were found to be non-isotropic in structure, the former having a marbled appearance under the polarising light microscope, and the latter showing numerous needle-shaped crystals. At loading above ...

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Item type:Article
Date:1992
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Identification Number:
ValueType
10.1016/0168-3659(92)90182-QDOI
Keywords:Polyacrylate polymer; Surfactant; Diffusion
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:9015
Owner only: item control page

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