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Kid-1, a putative renal transcription factor: regulation during ontogeny and in response to ischemia and toxic injury

URN to cite this document:
urn:nbn:de:bvb:355-epub-91980
Witzgall, Ralph ; O'Leary, Eileen ; Gessner, Reinhard ; Ouellette, Andre J. ; Bonventra, Joseph V.
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Date of publication of this fulltext: 06 Dec 2010 09:15


Abstract (German)

We have identified a new putative transcription factor from the rat kidney, termed Kid-1 (for kidney, ischemia and developmentally regulated gene 1). Kid-1 belongs to the C2H2 class of zinc finger genes. Its mRNA accumulates with age in postnatal renal development and is detected predominantly in the kidney. Kid-1 mRNA levels decline after renal injury secondary to ischemia or folic acid ...

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