GLUT1 is required for hyperglycemia-induced CaMKII activation

Hegner, Philipp , Baier, Maria J. , Krammer, Thomas, Seitz, Simon, Käs, Anna-Katharina, Zschiedrich, Tilman, Lukas, David, Lutz, Vanessa, Wolf, Matthias, Sinha, Frederick, Schopka, Simon , Schmid, Christof, Kozakov, Kostiantyn , Provaznik, Zdenek , Maier, Lars S. , Mustroph, Julian und Wagner, Stefan (2026) Semaglutide improves contractile function in human atrial myocardium of patients with heart failure and preserved ejection fraction. Cardiovascular Research 122 (6), S. 675-677.

Krammer, Thomas, Baier, Maria J. , Lutz, Vanessa, Hübner, Anna‐Christina, Zschiedrich, Tilman, Lukas, David, Le Phu, Christian, Wolf, Matthias, Maassen, Claire, Wester, Michael , Neef, Stefan, Schach, Christian , Sag, Can‐Martin, Evert, Katja , Paulus, Michael , Meindl, Christine , Tafelmeier, Maria , Debl, Kurt, Maier, Lars S. , Wagner, Stefan , Röcken, Christoph und Mustroph, Julian (2025) Left ventricular transthyretin amyloid load and apical sparing in patients with newly confirmed transthyretin amyloid cardiomyopathy. European Journal of Heart Failure.

Krammer, Thomas, Baier, Maria J. , Hegner, Philipp , Zschiedrich, Tilman, Lukas, David, Wolf, Matthias, Le Phu, Christian, Lutz, Vanessa, Evert, Katja , Kozakov, Kostiantyn , Li, Jing, Holzamer, Andreas , Maier, Lars S. , Provaznik, Zdenek , Bers, Donald M., Wagner, Stefan und Mustroph, Julian (2025) Cardioprotective effects of semaglutide on isolated human ventricular myocardium. European Journal of Heart Failure.

Pabel, Steffen, Wagner, Stefan , Bollenberg, Hannah, Bengel, Philipp, Kovács, Árpád, Schach, Christian , Tirilomis, Petros, Mustroph, Julian , Renner, André, Gummert, Jan, Fischer, Thomas, Van Linthout, Sophie, Tschöpe, Carsten, Streckfuss-Bömeke, Katrin, Hasenfuss, Gerd, Maier, Lars S. , Hamdani, Nazha und Sossalla, Samuel (2018) Empagliflozin Directly Improves Diastolic Function in Human Heart Failure. European Journal of Heart Failure 20 (12), S. 1690-1700. Volltext nicht vorhanden.

Sag, Can M., Wolff, Hendrik A., Neumann, Kay, Opiela, Marie-Kristin, Zhang, Juqian, Steuer, Felicia, Sowa, Thomas, Gupta, Shamindra N., Schirmer, Markus, Hünlich, Mark, Rave-Fränk, Margret, Hess, Clemens F., Anderson, Mark E., Shah, Ajay M., Christiansen, Hans und Maier, Lars S. (2013) Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII. Basic Research in Cardiology 108, S. 385. Volltext nicht vorhanden.

Purohit, Anil, Rokita, Adam G., Guan, Xiaoqun, Chen, Biyi, Koval, Olha M., Voigt, Niels, Neef, Stefan, Sowa, Thomas, Gao, Zhan, Luczak, Elizabeth D. , Stefansdottir, Hrafnhildur, Behunin, Andrew C., Li, Na, El-Accaoui, Ramzi N., Yang, Baoli, Swaminathan, Paari Dominic, Weiss, Robert M., Wehrens, Xander H.T., Song, Long-Sheng , Dobrev, Dobromir, Maier, Lars S. und Anderson, Mark E. (2013) Oxidized Ca 2+ /Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation. Circulation 128 (16), S. 1748-1757. Volltext nicht vorhanden.

Fischer, Thomas H., Herting, Jonas, Tirilomis, Theodor, Renner, André, Neef, Stefan, Toischer, Karl, Ellenberger, David , Förster, Anna, Schmitto, Jan D. , Gummert, Jan, Schöndube, Friedrich A., Hasenfuss, Gerd, Maier, Lars S. und Sossalla, Samuel (2013) Ca 2+ /Calmodulin-Dependent Protein Kinase II and Protein Kinase A Differentially Regulate Sarcoplasmic Reticulum Ca 2+ Leak in Human Cardiac Pathology. Circulation 128 (9), S. 970-981. Volltext nicht vorhanden.

Neef, Stefan und Maier, Lars S. (2013) Novel aspects of excitation–contraction coupling in heart failure. Basic Research in Cardiology 108, S. 360. Volltext nicht vorhanden.

Sag, Can M., Wagner, Stefan und Maier, Lars S. (2013) Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes. Free Radical Biology and Medicine 63, S. 338-349. Volltext nicht vorhanden.

Toischer, Karl, Hartmann, Nico, Wagner, Stefan , Fischer, Thomas H., Herting, Jonas, Danner, Bernhard C., Sag, Can M., Hund, Thomas J., Mohler, Peter J., Belardinelli, Luiz, Hasenfuss, Gerd, Maier, Lars S. und Sossalla, Samuel (2013) Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease. Journal of Molecular and Cellular Cardiology 61, S. 111-122. Volltext nicht vorhanden.

Maier, Lars S. , Layug, Beth, Karwatowska-Prokopczuk, Ewa, Belardinelli, Luiz, Lee, Stella, Sander, Julia, Lang, Christian, Wachter, Rolf , Edelmann, Frank , Hasenfuss, Gerd und Jacobshagen, Claudius (2013) RAnoLazIne for the Treatment of Diastolic Heart Failure in Patients With Preserved Ejection Fraction. JACC: Heart Failure 1 (2), S. 115-122. Volltext nicht vorhanden.

Maier, Lars S. und Sossalla, Samuel (2013) The late Na current as a therapeutic target: Where are we? Journal of Molecular and Cellular Cardiology 61, S. 44-50.

Hamdani, Nazha, Krysiak, Judith, Kreusser, Michael M., Neef, Stefan, dos Remedios, Cristobal G., Maier, Lars S. , Krüger, Markus, Backs, Johannes und Linke, Wolfgang A. (2013) Crucial Role for Ca 2+ /Calmodulin-Dependent Protein Kinase-II in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation. Circulation Research 112 (4), S. 664-674. Volltext nicht vorhanden.

Fischer, Thomas H., Neef, Stefan und Maier, Lars S. (2012) The Ca-calmodulin dependent kinase II: A promising target for future antiarrhythmic therapies? Journal of Molecular and Cellular Cardiology 58, S. 182-187.

Rasenack, Eva C. L., Oehler, Martin, Elsässer, Albrecht, Schilling, Meinhard und Maier, Lars S. (2012) Evaluation of a novel portable capacitive ECG system in the clinical practice for a fast and simple ECG assessment in patients presenting with chest pain: FIDET (Fast Infarction Diagnosis ECG Trial). Clinical Research in Cardiology 102 (3), S. 179-184. Volltext nicht vorhanden.

Fischer, Thomas H., Maier, Lars S. und Sossalla, Samuel (2012) The ryanodine receptor leak: how a tattered receptor plunges the failing heart into crisis. Heart Failure Reviews 18 (4), S. 475-483. Volltext nicht vorhanden.

Wagner, Stefan, Rokita, Adam G., Anderson, Mark E. und Maier, Lars S. (2012) Redox Regulation of Sodium and Calcium Handling. Antioxidants & Redox Signaling 18 (9), S. 1063-1077.

Maier, Lars S. (2012) Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) in the Heart. In: Islam, Md. Shahidul, (ed.) Calcium Signaling. Advances in Experimental Medicine and Biology, 740. Springer, Dordrecht, S. 685-702. ISBN 978-94-007-2888-2. Volltext nicht vorhanden.

Weil, Mareike B., Oehler, Martin, Schilling, Meinhard und Maier, Lars S. (2011) First clinical evaluation of a novel capacitive ECG system in patients with acute myocardial infarction. Clinical Research in Cardiology 101 (3), S. 165-174. Volltext nicht vorhanden.

Jacobshagen, Claudius, Belardinelli, Luiz, Hasenfuss, Gerd und Maier, Lars S. (2011) Ranolazine for the Treatment of Heart Failure With Preserved Ejection Fraction: Background, Aims, and Design of the RALI‐DHF Study. Clinical Cardiology 34 (7), S. 426-432. Volltext nicht vorhanden.

Neef, Stefan, Dybkova, Nataliya, Sossalla, Samuel , Ort, Katharina R., Fluschnik, Nina, Neumann, Kay, Seipelt, Ralf, Schöndube, Friedrich A., Hasenfuss, Gerd und Maier, Lars S. (2010) CaMKII-Dependent Diastolic SR Ca 2+ Leak and Elevated Diastolic Ca 2+ Levels in Right Atrial Myocardium of Patients With Atrial Fibrillation. Circulation Research 106 (6), S. 1134-1144. Volltext nicht vorhanden.

Jacobshagen, Claudius, Pax, Anja, Unsöld, Bernhard W., Seidler, Tim , Schmidt-Schweda, Stephan, Hasenfuss, Gerd und Maier, Lars S. (2009) Effects of large volume, ice-cold intravenous fluid infusion on respiratory function in cardiac arrest survivors. Resuscitation 80 (11), S. 1223-1228. Volltext nicht vorhanden.

Sag, Can M., Wadsack, Daniel P., Khabbazzadeh, Sepideh, Abesser, Marco, Grefe, Clemens, Neumann, Kay, Opiela, Marie-Kristin, Backs, Johannes, Olson, Eric N., Brown, Joan Heller, Neef, Stefan, Maier, Sebastian K.G. und Maier, Lars S. (2009) Calcium/Calmodulin-Dependent Protein Kinase II Contributes to Cardiac Arrhythmogenesis in Heart Failure. Circulation: Heart Failure 2 (6), S. 664-675. Volltext nicht vorhanden.

Wagner, Stefan , Hacker, Elena, Grandi, Eleonora, Weber, Sarah L., Dybkova, Nataliya, Sossalla, Samuel , Sowa, Thomas, Fabritz, Larissa, Kirchhof, Paulus, Bers, Donald M. und Maier, Lars S. (2009) Ca/Calmodulin Kinase II Differentially Modulates Potassium Currents. Circulation: Arrhythmia and Electrophysiology 2 (3), S. 285-294. Volltext nicht vorhanden.

Neef, Stefan und Maier, Lars S. (2008) Remodeling of excitation-contraction coupling in the heart: Inhibition of sarcoplasmic reticulum Ca2+ leak as a novel therapeutic approach. Current Heart Failure Reports 4, S. 11-17. Volltext nicht vorhanden.

Hasenfuss, Gerd und Maier, Lars S. (2008) Inhibition of the Late Sodium Current with Ranolazine – A New Cardioprotective Mechanism. European Cardiology Review 4 (2), S. 46. Volltext nicht vorhanden.

Sag, Can M., Dybkova, Nataliya, Neef, Stefan und Maier, Lars S. (2007) Effects on recovery during acidosis in cardiac myocytes overexpressing CaMKII. Journal of Molecular and Cellular Cardiology 43 (6), S. 696-709. Volltext nicht vorhanden.

Guan, Kaomei , Wagner, Stefan , Unsöld, Bernhard, Maier, Lars S. , Kaiser, Diana, Hemmerlein, Bernhard, Nayernia, Karim, Engel, Wolfgang und Hasenfuss, Gerd (2007) Generation of Functional Cardiomyocytes From Adult Mouse Spermatogonial Stem Cells. Circulation Research 100 (11), S. 1615-1625. Volltext nicht vorhanden.

Yurukova, Sevdalina, Kilić, Ana, Völker, Katharina, Leineweber, Kirsten, Dybkova, Nataliya, Maier, Lars S. , Brodde, Otto-Erich und Kuhn, Michaela (2007) CaMKII-mediated increased lusitropic responses to β-adrenoreceptor stimulation in ANP-receptor deficient mice. Cardiovascular Research 73 (4), S. 678-688. Volltext nicht vorhanden.

Maier, Lars S. , Bers, Donald M. und Brown, Joan Heller (2007) Calmodulin and Ca2+/calmodulin kinases in the heart – Physiology and pathophysiology. Cardiovascular Research 73 (4), S. 629-630. Volltext nicht vorhanden.

Maier, Lars S. , Teucher, Nils, Dorge, H und Konstantinides, Stavros (2007) Large emboli on their way through the heart – First live demonstration of large paradoxical embolisms through a patent foramen ovale. European Journal of Echocardiography 8 (2), S. 158-160. Volltext nicht vorhanden.

Maier, Lars S. und Bers, Donald M. (2007) Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation–contraction coupling in the heart. Cardiovascular Research 73 (4), S. 631-640. Volltext nicht vorhanden.

Grandi, Eleonora, Puglisi, Jose L., Wagner, Stefan , Maier, Lars S. , Severi, Stefano und Bers, Donald M. (2007) Simulation of Ca-Calmodulin-Dependent Protein Kinase II on Rabbit Ventricular Myocyte Ion Currents and Action Potentials. Biophysical Journal 93 (11), S. 3835-3847. Volltext nicht vorhanden.

Maier, Lars S. , Buchwald, Arnd B., Ehlers, Björn, Rühmkorf, Klaus und Scholz, Karl H. (2002) Closure of an iatrogenic aortocoronary arteriovenous fistula: Transcatheter balloon embolization following failed coil embolization and salvage of coils that migrated into the coronary venous system. Catheterization and Cardiovascular Interventions 55 (1), S. 109-112. Volltext nicht vorhanden.

Maier, Lars S. , Bers, Donald M. und Pieske, Burkert M. (2002) Differences in Ca2+-Handling and Sarcoplasmic Reticulum Ca2+-Content in Isolated Rat and Rabbit Myocardium. Journal of Molecular and Cellular Cardiology 32 (12), S. 2249-2258. Volltext nicht vorhanden.

Weisser, Jutta, Martin, Jürgen, Bisping, Egbert, Maier, Lars S. , Beyersdorf, Friedhelm, Hasenfuss, Gerd und Pieske, Burkert M. (2001) Influence of mild hypothermia on myocardial contractility and circulatory function. Basic Research in Cardiology 96, S. 198-205. Volltext nicht vorhanden.