Angerer, Erwin von and Prekajac, Jelica (1983) 2-(Hydroxyphenyl)indoles: a new class of mammary tumor-inhibiting compounds. Journal of Medicinal Chemistry 26 (1), pp. 113-116.
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l-Allryl-4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-6-hydroxyindo(l4e,as l kyl =i CHa, CsHs, CaH,) were synthesized by thermolysis of the corresponding NJV’-dialkyl-1,2-diphenylethylenediamineasn d subsequent ether cleavage. They showed an affinity for the estrogen receptor (1% of 178-estradiol) and inhibited the growth of the 9,lO-dimethyl- l,2-benz[u]anthracene (DMBA) induced mammary carcinoma ...
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|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||17 May 2010 12:11|
|Last Modified:||13 Mar 2014 13:28|