Lowe, W. and Elz, Sigurd and Reiser, H. and Schott, S. (1994) [7-fluoro-4-chromone-3-sulfur compounds]. Archiv der Pharmazie 327 (4), pp. 267-269.
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The novel 7-fluoro-4-chromone-3-sulfur compounds 5-12 were synthesized from the sulfinic acid 4, which can be obtained from the enaminone 3 and thionyl chloride. Especially the Flosequinane-like sulfoxide 12 was prepared and the vasodilating activity was evaluated in isolated ring segments of rat aorta.
|Additional information (public):||Lowe, W Elz, S Reiser, H Schott, S English Abstract In Vitro Germany Archiv der Pharmazie Arch Pharm (Weinheim). 1994 Apr;327(4):267-9.|
|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz)|
|Keywords:||Animals Aorta, Thoracic/drug effects Chromones/*chemical synthesis/pharmacology Male Muscle, Smooth, Vascular/drug effects Rats Rats, Wistar Vasodilator Agents/*chemical synthesis/pharmacology|
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||No|
|Owner:||Prof. Dr. Sigurd Elz|
|Deposited On:||19 Oct 2010 12:22|
|Last Modified:||19 Oct 2010 12:22|