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Genes optimized by evolution for accurate and fast translation encode in Archaea and Bacteria a broad and characteristic spectrum of protein functions

von Mandach, Conrad and Merkl, Rainer (2010) Genes optimized by evolution for accurate and fast translation encode in Archaea and Bacteria a broad and characteristic spectrum of protein functions. BMC genomics 11 (1), p. 617.

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Abstract

BACKGROUND: In many microbial genomes, a strong preference for a small number of codons can be observed in genes whose products are needed by the cell in large quantities. This codon usage bias (CUB) improves translational accuracy and speed and is one of several factors optimizing cell growth. Whereas CUB and the overrepresentation of individual proteins have been studied in detail, it is still ...

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Item Type:Article
Date:4 November 2010
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner > Arbeitsgruppe PD Dr. Rainer Merkl
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
21050470PubMed ID
10.1186/1471-2164-11-617DOI
Subjects:500 Science > 570 Life sciences
000 Computer science, information & general works > 004 Computer science
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Nov 2010 14:01
Last Modified:13 Mar 2014 17:25
Item ID:17985
Owner Only: item control page

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