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Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y

Wiedemann, Sonja M. and Mildner, Silke N. and Bönisch, Clemens and Israel, Lars and Maiser, Andreas and Matheisl, Sarah and Straub, Tobias and Merkl, Rainer and Leonhardt, Heinrich and Kremmer, Elisabeth and Schermelleh, Lothar and Hake, Sandra B. (2010) Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. The Journal of cell biology 190 (5), pp. 777-791.

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Abstract

Nucleosomal incorporation of specialized histone variants is an important mechanism to generate different functional chromatin states. Here, we describe the identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. Their messenger RNAs are found in certain human cell lines, in addition to several normal and malignant human tissues. In keeping with their ...

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Item Type:Article
Date:2010
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner > Arbeitsgruppe PD Dr. Rainer Merkl
Identification Number:
ValueType
20819935PubMed ID
10.1083/jcb.201002043DOI
Subjects:500 Science > 570 Life sciences
000 Computer science, information & general works > 004 Computer science
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Rainer Merkl
Deposited On:15 Nov 2010 13:57
Last Modified:15 Nov 2010 13:57
Item ID:17986
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