Go to content
UR Home

Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools

Keller, Max and Erdmann, Daniela and Teng, Shangjun and Pop, Nathalie and Pluym, Nikola and Bernhardt, Günther and Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools. Bioorganic & Medicinal Chemistry 19 (9), pp. 2859-2878.

Full text not available from this repository.

at publisher (via DOI)

at PubMed

Other URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TF8-52FVDD4-4&_user=616165&_coverDate=05%2F01%2F2011&_alid=1736037942&_rdoc=2&_fmt=high&_orig=search&_origin=search&_zone=rslt_list_item&_cdi=5220&_sort=r&_st=13&_docanchor=&view=c&_ct=3&_acct=C00


Fluorescently labelled NPY Y1 receptor (Y1R) ligands were synthesized by connecting pyrylium and cyanine dyes with the argininamide-type Y1R antagonist core structure by linkers, covering a wide variety in length and chemical nature, attached to the guanidine group. The most promising fluorescent probes had Y1R affinities (radioligand binding) and antagonistic activities (calcium assay) in the ...


Export bibliographical data

Item Type:Article
Date:16 March 2011
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
21493077PubMed ID
Related URLs:
http://www.sciencedirect.com/science/MiamiMultiMediaURL/B6TF8-52FVDD4-4/B6TF8-52FVDD4-4-1/5220/html/S0968089611002264/f82d36d5aa7b84bc4647c190c530e20f/mmc1.pdfSupplementary Material
Keywords:NPY Y1 receptor; fluorescent ligands; Y1R binding; Y1R antagonism; argininamide derivatives; confocal microscopy; flow cytometry
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:24 Mar 2011 07:19
Last Modified:30 Apr 2011 14:46
Item ID:18611
Owner Only: item control page
  1. Homepage UR

University Library

Publication Server

Contact person
Gernot Deinzer

Phone +49 941 943-2759