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The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy

Liebold, Christoph and List, Felix and Kalbitzer, Hans Robert and Sterner, Reinhard and Brunner, Eike (2010) The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy. Protein science : a publication of the Protein Society 19 (9), pp. 1774-1782.

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Abstract

The imidazole glycerol phosphate (ImGP) synthase from the hyperthermophilic bacterium Thermotoga maritima is a 1:1 complex of the glutaminase subunit HisH and the cyclase subunit HisF. It has been proposed that ammonia generated by HisH is transported through a channel to the active site of HisF, which generates intermediates of histidine (ImGP) and de novo biosynthesis of ...

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Item Type:Article
Date:2010
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner
Identification Number:
ValueType
20665694PubMed ID
10.1002/pro.463DOI
Classification:
NotationType
Aminohydrolases/metabolismMESH
Ammonia/metabolismMESH
Binding SitesMESH
Models, MolecularMESH
Nuclear Magnetic Resonance, Biomolecular/methodsMESH
Thermotoga maritima/metabolismMESH
Xenon/metabolismMESH
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:03 May 2011 06:00
Last Modified:03 May 2011 06:00
Item ID:20752
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