Müller, R. H. and Lherm, C. and Herbort, J. and Blunk, Torsten and Couvreur, P.
Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length.
International Journal of Pharmaceutics 84 (1), pp. 1-11.
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Alkylcyanoacrylate particles were physico-chemically characterized in terms of size, surface charge, zeta potential, interaction with charged serum components and surface hydrophobicity as relevant parameters influencing the in vitro interaction with cells in culture and the in vivo organ distribution and fate after intravenous administration. Methyl-, ethyl-, isobutyl- and isohexyl-cyanoacrylate ...
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