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ATP-binding cassette transporters in immortalised human brain microvascular endothelial cells in normal and hypoxic conditions

Lindner, Christian and Sigrüner, Alexander and Walther, Franziska and Bogdahn, Ulrich and Couraud, Pierre O. and Schmitz, Gerd and Schlachetzki, Felix (2012) ATP-binding cassette transporters in immortalised human brain microvascular endothelial cells in normal and hypoxic conditions. Experimental & Translational Stroke Medicine 4, p. 9.

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Abstract

Background Rapid reperfusion following ischemia is the most effective therapy in stroke therapy. However, the success may be compromised by ischemia & reperfusion (I/R) injury and at the human blood-brain barrier (BBB), therefore the effects on transendothelial transport are of special interest. Current studies suggest the ATP-binding cassette (ABC) transporters to be regulated upon ischemic ...

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Item Type:Article
Date:3 May 2012
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Medicine > Lehrstuhl für Neurologie
Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/2040-7378-4-9DOI
Keywords:Blood–brain barrier; Ischemia/reperfusion injury; Hypoxia-inducible factor; Multidrug resistance; ABC transporters; Stroke
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Universitätsbibliothek Regensburg
Deposited On:07 Sep 2012 06:48
Last Modified:13 Mar 2014 19:58
Item ID:25847
Owner Only: item control page

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