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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-267166
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.26716
Zusammenfassung
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only. Yet the catalytic site of EF was recently shown to accomplish cyclization of cytidine 5'-triphosphate, uridine 5'-triphosphate and inosine 5'-triphosphate, in addition to adenosine 5'-triphosphate. This review discusses the broad EF ...
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