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Quantitation of hyaluronidases by the Morgan-Elson reaction: comparison of the enzyme activities in the plasma of tumor patients and healthy volunteers

Muckenschnabel, Ingo and Bernhardt, Günther and Spruß, Thilo and Dietl, Barbara and Buschauer, Armin (1998) Quantitation of hyaluronidases by the Morgan-Elson reaction: comparison of the enzyme activities in the plasma of tumor patients and healthy volunteers. Cancer Letters 131, pp. 13-20.

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Other URL: doi:10.1016/S0304-3835%2898%2900196-7


Abstract

The Morgan-Elson reaction, a method for the detn. of hyaluronidase activity, was optimized for the quantitation of the enzyme in biol. material. Based on HPLC and spectrometric (UV-Vis, LC-MS) studies, the structure of the red-colored product (mesomeric forms of N3-protonated 3-acetylimino-2-(4-dimethylaminophenyl)methylidene-5-(1,2-dihydroxyethyl)furane) formed by condensation of chromogen III ...

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Item Type:Article
Date:1998
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:22 Feb 2008 13:18
Last Modified:05 Aug 2009 13:42
Item ID:3417
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